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We report mapping of the mutation for this syndrome, and further report identification of a novel, phenotypically reciprocal mutation in the same molecular pathway, defining the slick coated, thermotolerant characteristics of the Senepol breed of cattle.ResultsA novel pleiotropic syndrome in dairy cattleAs part of routine animal screening in https://www.cheapjerseys13.com a large dairy cattle breeding programme in New Zealand, we identified a dominant genetic syndrome that had been rapidly propagated through the population through widespread use of semen representing a bull and his son. Animals within the pedigree (N>6,000) segregated for abnormally long and 'hairy' coats, symptoms of heat stress including increased respiration rates and the tendency to wallow in mud and drinking troughs, and major defects in lactation. Detailed examination of 12 affected and 12 control females showed that hair was more slender (two sided t test, P=1.4104) and approximately twice as long in affected animals (two sided t test, P=1.4 107; Fig.
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